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The downside is that the population may not be representative of the overall population since it is made of veterans (for example, 95% male)

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Notably, a series of emerging mechanisms, such as the VDR/FFAR2 (Xu et al., 2024) axis and HIF-1/LDHA axis (Kuang et al., 2025), have been confirmed as key pathways regulating cellular ferroptosis sensitivity

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