If you have not achieved the required weight loss, the renewal may be denied
Presented by Klara Rachel Klein, MD, PhD (University of North Carolina School of Medicine, Chapel Hill), at the American Diabetes Association (ADA) 2026 Scientific Sessions in New Orleans, the randomized, double-blind, 27-site trial compared HDV-LIS (n=112) with standard insulin lispro (n=114) in 226 adults with T1D, all on insulin degludec and a Dexcom G7 CGM
Your healthcare provider can help match the best option to your medical needs and financial situation
Nausea was reported at nearly identical rates (approximately 44%) for both drugs in comparative analyses
For researchers concerned about cardiovascular risk, practical strategies to minimize TMAO production include supporting a healthy gut microbiome through prebiotic and probiotic use, monitoring TMAO levels if testing is available, and keeping total levocarnitine exposure within studied safety ranges