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Data availability The data generated in this study are available from the corresponding author upon reasonable request

The tumor tissue of osteosarcoma was obtained, cut into small fragment, and transplanted subcutaneously into BALB/c nude mice

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5-Amino-1MQ capsules contain a high-purity synthetic compound designed to inhibit nicotinamide N-methyltransferase (NNMT), playing a key role in metabolic regulation and energy homeostasis

Protective Clothing : Advise wearing hats, sunglasses, and protective clothing when outdoors