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As access to compounded GLP-1 injections recently became increasingly restricted, many patients turned to the gray market an underground network where medications are sold outside regulated pharmacies

Similarly, for Zepbound (tirzepatide), fatigue was reported in 7.2-10.8% of patients (depending on dose) versus 4.1% in the placebo group

Interestingly, fatigue and tiredness are reported far more commonly than insomnia

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If measurement of tirzepatide were needed for research purposes, specialized reference laboratories would typically analyze serum or plasma samples using targeted assays, but this is not part of any standard testing panel