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These potential applications are supported by small RCTs and mechanistic studies indicating ECM remodeling, antioxidant effects, and anti-inflammation [1, 2, 3, 5, 8]

it's a critical, non-negotiable element of scientific rigor

Iptakalim inhibits nicotinic acetylcholine receptor-mediated currents in dopamine neurons acutely dissociated from rat substantia nigra pars compacta

Moreover, the limited bioavailability, poor water solubility, and chemical instability of resveratrol strongly restrict its in vivo biological effects [83]