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A separate narrative review titled "Regeneration or Risk?" acknowledged the promising preclinical evidence but stressed the critical need for larger human trials

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There's a higher risk of post-inflammatory hyperpigmentation (PIH), which means the treated area could become darker than the surrounding skin

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NAD+ can change how certain cancer treatments work and might reduce insulin sensitivity [24]

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Gupta and DuBois, 1998

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53 Another study used the same stereotactic method and transplanted MSCs into the brains of mice with Parkinsons disease

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