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DPP 4 inhibitors are associated with a lower risk of hypoglycaemia compared to some other diabetes medications, making them an attractive option for individuals who are at risk of low blood sugar

[29] Combination drugs [edit] Some DPP-4 inhibitor drugs have received approval from the FDA to be used with metformin concomitantly with additive effect to increase the level of glucagon-like peptide 1 (GLP-1) which also decreases hepatic glucose production