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All subjects were observed and assessed for side effects such as changes in alertness and general activity, the presence of excessive salivation, gagging, and regurgitation following each injection until the end of the experimental day (4 pm)

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This also means it may not be ideal for everyone

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Van der Paal, J., Neyts, E

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After the inactivation of iNOS, M1 macrophages were less resistant to ferroptosis [45], while after transfection of the iNOS plasmid into M2 macrophages, their ferroptosis resistance was significantly enhanced

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Its been FDA-approved for this use since 2017

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