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Pharmaceutical medications NSAIDs caution: Non-steroidal anti-inflammatory drugs (ibuprofen, naproxen) may impair bone healing if used excessively especially early post-fracture

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Passive accumulation and the enhanced permeability and retention effect remain the baseline mechanisms for tumor localization in most nanoplatforms, but they are subject to substantial variability between tumors and even within the same lesion [55, 56]