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Collectively, these evidence supports the hypothesis that NaIO 3 -induced ROS caused the damage to RPE cells by ferroptosis
The antioxidant effect of GPX4 depends on the presence of GSH as a reducing agent, with two GSH reducing one LOOH
doi: 10.1146/annurev-nutr-082117-051732 35 CassatJESkaarEP
observed the repressed expression of GPX4 in the mitochondria of RGCs, concomitant with elevated levels of mt-ROS (62)
Influence of sickle cell disease and treatment with hydroxyurea on sperm parameters and fertility of human males
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