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Risk Factors for Dementia Certain physical and lifestyle factors can raise your chances of dementia, including: Your age Family history of dementia Illnesses including diabetes, Down syndrome, multiple sclerosis, heart disease, and sleep apnea Depression Lifestyle factors, such as smoking, heavy alcohol use, poor diet, and lack of exercise Brain injury from accidents, high-impact sports, and military service Strokes Infection of the brain (for example, meningitis and syphilis) Hearing loss Low levels of some vitamins and nutrients such as vitamins D and B12 Sleep problems and disorders, including insomnia or dependence on sleep medications Pollutants in your environment Cognitive reserve, which is your brain's ability to handle diseases and comes from doing mentally stimulating work Benadryl and dementia Benadryl belongs to a class of medicines called anticholinergics

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