To evaluate the impact of these NRF2 target genes on TNBC prognosis, we plotted the significance (log 10 of p-values) of logrank tests for DEGs downregulated by Cyss depletion using the Kaplan-Meier plotter platform and based on relapse-free survival ( RFS) and distant metastasis-free survival (DMFS) as endpoints of patients with TNBC and ER+/PR+, ER+/PR, and ER/PR/Her+ non-TNBC [27]
Additionally, certain nutrients like vitamin C, vitamin E, and selenium also play supportive roles in maintaining healthy glutathione levels
Caspase, growth regulatory, and DNA repair genes are important in cancer suppression
Plant extracts and their metabolites can also lower HTN through their anti-inflammatory effects (48)
SUMMARY The invention provides small molecule mimetics (mimic) of the growth factor "hepatocyte growth factor" (HGF) that are orally active, display profound growth factor activity, and are inexpensive to synthesize