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These reports exist, and theyre concerning to the individuals who experienced them

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2017;8 doi: 10.1128/mBio.00646-17

It can be found that compared with the Model group, the Low group and High group secreted more insulin after berberine treatment (Figure 1I), and calculated homeostatic model assessment of insulin resistance (HOMA-IR) index according to the following formula: HOMA-IR = FBG (mM) Fasting insulin (mU/L)/22.5 (Figure 1J)

Ask your healthcare provider first if its OK for you to take, but most people can add Vitamin C to their medication regimen