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Figure 4 FASN is a binding chaperone for GSDMD, and the interaction between FASN and GSDMD is only observed in LPS-stimulated macrophages (135)

Severe symptomatic hypoglycemia was defined as an event with symptoms consistent with hypoglycemia requiring the assistance of another person and associated with either a blood glucose below 50 mg/dL (56 mg/dL in the 5-year study and 36 mg/dL in the ORIGIN study) or prompt recovery after oral carbohydrate, intravenous glucose, or glucagon administration

Understanding the relationship between vial concentration, injection volume, and target dose is essential for proper reconstitution and administration

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