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In the HARMONY-2 (efficacy and safety of once-weekly GLP-1 receptor agonist albiglutide) clinical study, patients were randomized to receive either once-weekly albiglutide (30 mg, titrated up to 50 mg if required for glycemic control) or 10 units of insulin glargine once daily

Ethical Approval This study was based exclusively on aggregated, arm-level data extracted from previously published clinical trials

For refractory cases, the suggestion is to measure Co-Q10 levels in blood and increase the dose to reach a serum level of 3mg/L

B.PeriS.ThielkeA.BalachandranS.HolmC

Patience, combined with proactive skincare, can go a long way in managing this side effect