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Some early evidence suggests tirzepatide may actually improve mood and anxiety for certain people, though more research is needed to confirm this

Until now, every diet and every obesity pharmacotherapy ran into the bodys adaptive thermogenic response, the body defends against weight loss by slowing metabolism

The melanocortin 4 receptor (MC4R) is thought to be situated within the central nervous system, particularly in the hypothalamus

Heres why: Rapid weight loss (whether due to GLP-1s or otherwise) can increase the risk of losing lean muscle mass alongside body fat