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Exendin-4 was ultimately synthesized to Exenatide, a GLP-1RA with a half-life sufficient to permit clinical use in treating type 2 diabetes, the first in a new generation of drugs that followed

In parallel, several clinical studies were conducted and provided evidence that acetyl-l-carnitine may represent an effective therapeutic option for treating peripheral neuropathies (Table 1) [46,47,48,49,50,51,52]

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