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doi: 10.3389/fendo.2024.1520313 Received 31 October 2024 Accepted 26 December 2024 Published 21 January 2025 Volume 15 - 2024 Edited by Joseph M

GH & IGF-1 support Studied for stimulating pulsatile growth hormone release, pairing a ghrelin agonist with a GHRH analog to raise IGF-1

Niacinamide could enhance these effects by improving mitochondrial function and cellular energy metabolism, allowing tissues to respond more effectively to the metabolic signals initiated by tirzepatide