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Some individuals may struggle to absorb enough B12 from their diet, especially those with conditions like pernicious anemia, certain gastrointestinal disorders, or those taking medications that impact absorption

This parameter has been further studied, showing that those men and women in the lowest quartile of the IGF-1/IGFBP3 ratio are threefold more likely to meet the Adult Treatment Panel III (ATP-III) definition for MetS, and twice as likely to be insulin resistantthat IGF-1/IGFBP-3 ratio decreases notably as the number of MetS components increases [217]

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In fact, its thought that up to 88% of people following these diets have a deficiency ( This is because B12 is only found naturally in animal foods