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Vitamin B12 is absorbed in our small intestines

B12 shots are widely considered safe, but a few situations may require extra care

As such, patients with complex cases may still be considered under specific conditions

A recent study in postmortem tissue from SSD patients found regional shifts in the expression of cortical excitatory and inhibitory transcripts [72] and a previous study found alterations in regulators of NKCC1 and KCC2 [73], while animal models of other ASD-relevant gene mutations have also reported shifts in E/I balance [70]

In the severe cases where the temperature is greater than 41.1C, patients should be immediately paralysed and intubated, with nondepolarizing agents such as vecuronium to maintain paralysis