A recent study reported that suppression of HMGB1 could alleviate high glucose-induced ferroptosis in glomerular mesangial cells and ameliorate the progression of inflammation
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Pravat K Mandal, Anshika Goel, Ashley I Bush, Khushboo Punjabi, Shallu Joon, Ritwick Mishra, Manjari Tripathi, Arun Garg, Natasha K Kumar, Pooja Sharma, Deepika Shukla, Scott Jonathan Ayton, Amir Fazlollahi, Joseph C Maroon, Divya Dwivedi, Avantika Samkaria, Kanika Sandal, Kanu Megha, Sandhya Shandilya, Hippocampal glutathione depletion with enhanced iron level in patients with mild cognitive impairment and Alzheimers disease compared with healthy elderly participants, Brain Communications, Volume 4, Issue 5, 2022, fcac215, Watanabe F, Hashizume E, Chan GP, Kamimura A
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They may improve the quality of repaired tissue