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The peptide also promotes polarization of macrophages from pro-inflammatory M1 phenotypes toward tissue-repairing M2 phenotypes, with treated macrophages showing 70% increased phagocytic activity for clearing inflammatory debris and 3-fold higher production of VEGF compared to untreated controls

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Hypertrophic scarring: the greatest unmet challenge after burn injury

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It increases coronary blood flow and reduces vascular resistance, contributing to improved cardiac function and protection against ischemic injury [41]