dpp-4 and glp-1 together A Comprehensive Review on Dipeptidyl Peptidase-4 (DPP-4) Inhibitors: Mechanism, Therapeutic Applications, Future Perspectives Incretin axis and incretin-based therapies:

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Both agents lower blood glucose through different mechanisms, and their simultaneous use could theoretically increase the risk of hypoglycemia, particularly in patients taking other antidiabetic medications such as insulin or sulfonylureas