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Last reviewed: June 1, 2026 Last updated: June 1, 2026 Written by: Jay Hastings, CEO of PlexusDx Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations

The preservatives in the formulation, typically benzyl alcohol or phenol, are designed to handle some level of contamination

Underdosing blunts the metabolic signal

Solution: When less than 2 doses remain in a vial, consider starting a new vial for consistency

"I did initially gain about 10 pounds, but it kind of gave me that wake-up call of like, oh yeah, I need to be doing my healthy lifestyle habits and all those changes." "I just kind of refocused and made sure that I was making healthy choices," she said, describing how she has maintained her health post-semaglutide