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Thermo Fisher Scientific) into the peritoneum of mice recipients before lesion isolation, using a 27-gauge needle (Thermo Fisher Scientific)

In chemotherapy-sensitive patients, Keap1 (Kelch-like ECH-associated protein 1) binds to NRF2 and mediates NRF2 ubiquitination via the Cul3-E3 ligase complex, promoting its degradation and maintaining NRF2 at low levels [32]

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Its compounded semaglutide and tirzepatide preparations are not FDA-approved