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113 Subsequently, Syk was recruited to phosphorylated ITAM through the SH2 domain and activated, initiating downstream signal transduction, resulting in phosphorylation and activation of PI3K and effectors such as LAT, SLP-76, Gads, and jointly promoting phosphorylation and activation of PLC 2 and PKC

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INBio D24.2, E

doi: 10.33549/physiolres 21 BollePEvandriMGSasoL