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1995 Dec 29;771:240-51

It's addressing the metabolic dysfunction driving the oxidative load in the first place

The journey of understanding and utilizing these advanced pharmacological interventions marks a significant advance in our ability to combat obesity, paving the way for a healthier future for those affected

Gushen Jiedu capsule(GSJD)originated from the classic Chinese kidney tonic formula Shuilu Erxiandan in the Song Dynasty (1170 AD), which down-regulates pro-apoptotic protein Bcl-2-associated X protein (Bax) expression and up-regulates B cell lymphoma 2 (BCL-2) expression in the kidney of DN rats to regulate the mitochondrial apoptosis pathway

Targets the GHS-R1a (ghrelin) receptor Same receptor as ghrelin, located in the pituitary and hypothalamus