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No significant heterogeneity among studies ( I 2 = 0%, p =0.64), so the fixed-effects model was used to combine the effect sizes

Source: Musazadeh, Vali, Hanie Alinejad, Niloofar Kouhi Esfahani, Zeynab Kavyani, Majid Keramati, Neda Roshanravan, Erfan Mosharkesh, and Parvin Dehghan

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In published preclinical work, KPV has been studied for inhibiting NF-B activation in intestinal epithelial cells, with one widely cited study showing PepT1-mediated transport into colonic cells as part of its anti-inflammatory mechanism in mouse colitis models (Dalmasso et al., Gastroenterology , 2008)