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Because gastrointestinal absorption of protein-bound B can be impaired in patients on proton-pump inhibitors or metformin, parenteral or high-dose oral methylcobalamin offers a bioavailable alternative

Folate transport proteins mediate the bidirectional transport of 5-methyltetrahydrofolate in cultured human proximal tubule cells

Although fruits and vegetables can provide nutrients, they are insufficient to meet the bodys need for Vitamin C

The internalizing mechanism of CPPs is largely dependent on the properties of CPPs, cell types (membrane compositions and cellular machineries for uptake), transported cargos (concentration, structure, and linking methods), and the experimental conditions (pH and temperature) (Xie et al., 2020)

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