semaglutide indications Indication Opportunity: From CDK, HFpEF to Alzheimer's disease Weight Loss and Cardiovascular Events

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From Semaglutide and Tirzepatide reduce alcohol consumption in individuals with obesity: In the remote study, we observe a significantly lower self-reported intake of alcohol, drinks per drinking episode, binge drinking odds, Alcohol Use Disorders Identification Test (AUDIT) scores, and stimulating, and sedative effects in the Semaglutide or Tirzepatide group when compared to prior to starting medication timepoint (within-subjects) and the control group (between-subjects)

This experiment was motivated by the observation that tamoxifen inhibited bovine brain cAMP phosphodisterase

This difference compounds over months and can represent 10 to 15 additional pounds of fat loss over a year

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