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Common contraindications cited in the research-use community include: anyone with active or recent cancer (BPC-157 and TB-500 promote angiogenesis), people with Wilson's disease or other copper-metabolism disorders (GHK-Cu component), anyone pregnant or breastfeeding (no safety data), and athletes subject to WADA testing (BPC-157 and TB-500 are prohibited)

In parallel with these clinical advances, the growth of academic output has been striking

While not currently prohibited, WADA is tracking whether these medications are being misused in sports contexts

It supports the vascular supply to peripheral tissue at a time when circulation may be a limiting factor

Furthermore, in addition to incretin hormones, DPP-4 cleaves many other non-incretin peptides and regulates various biological processes