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For example, in cancer, combining HSP90 inhibitors with autophagy inhibitors could lead to the accumulation of misfolded proteins and induce cell death

Summary: The adoption of these technologies and the establishment of novel therapeutic interventions is difficult since there is a gap in terms of a complete understanding of the pathophysiological mechanisms at the cellular and molecular level and the lack of data in terms of the assessment of safety and bioavailability differences in the individuals patients

Flavin-containing monooxygenase 3 (FMO3): genetic variants and their consequences for drug metabolism and disease

J Parasit Dis 45:474478

Biosynthesis : It provides carbon and nitrogen for building nucleotides, lipids, and proteins