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Ochronosis was most often reported in middle-aged women (53.2%), of African descent (45.2%), Black races (55.5%), and Fitzpatrick skin types V-VI (52.4%)

Suspected adverse reactions should be reported through the MHRA Yellow Card scheme (yellowcard.mhra.gov.uk or via the Yellow Card app), contributing to ongoing medication safety surveillance

In many cases, it complements existing therapies by addressing the neurological component of sexual desire, while other treatments address hormonal, metabolic, or emotional factors

Straszewski-Chavez, S

It was originally isolated from human plasma in 1973 and has accumulated extensive peer-reviewed preclinical research over five decades