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However, the parenteral use of vitamin B12 has proven itself not only in pernicious anemia, the classic B12 deficiency disease, but also in polyneuropathies and mental disorders

Similarly, brown adipose tissue (BAT) undergoes a fuel shift from glucose to fatty acid and amino acid metabolism during cold adaptation, facilitating thermogenesis to maintain body temperature ( 36 )

Female patients, smokers, gastric and mixed ulcer patients, patients with GERD or chronic diseases, subjects with chronic NSAIDs intake or regular intake of acid-inhibitory drugs, antibiotics or antioxidants in the preceding one month of the study