glp 1 always cold Feeling extra lately? ❄️ If you’re on a GLP-1 medication, you’re not imagining it! A lesser-known side effect is increased cold sensitivity—likely due to fat loss and metabolic changes. 🥶 , But Why do GLP-1s do this?

Most GLP-1 medicines are administered via subcutaneous injection, either daily or weekly depending on the specific formulation, though oral semaglutide (Rybelsus) is also available

doi: 10.3389/fphar.2023.1191290 Received 22 March 2023 Accepted 28 July 2023 Published 08 August 2023 Volume 14 - 2023 Edited by Yusof Kamisah, Universiti Kebangaan Malaysia, Malaysia Reviewed by Patrick Orlando, Marche Polytechnic University, Italy Hana Rauchov, Academy of Sciences of the Czech Republic (ASCR), Czechia Iain Hargreaves, Liverpool John Moores University, United Kingdom Updates Copyright 2023 Dabbaghi Varnousfaderani, Musazadeh, Ghalichi, Kavyani, Razmjouei, Faghfouri, Ahrabi, Seyyed Shoura and Dehghan

To minimize the occurrence and severity of side effects, healthcare providers often recommend starting with a low dose of the medication and gradually increasing it to the target dose

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However, modest increases in resting heart rate consistently appear across GLP-1 trials, typically averaging 2 to 4 beats per minute