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It increases the risk for multiple metabolic complications including type 2 diabetes (T2D), metabolic-dysfunction associated steatotic liver disease (MASLD, previously known as non-alcoholic fatty liver disease), cardiovascular disease as well as many mechanical complications such as osteoarthritis and obstructive sleep apnoea (OSA) [3]

microdosing begins at lower doses of 1.5 mg for women and 1.8 mg for men

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However, rare and severe complications may also develop in children, with a systemic involvement due to a multisystem inflammatory syndrome (MIS-C) (120)

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