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L-Citrulline L-Citrulline is converted to L-arginine in the ureanitric oxide cycle, supporting nitric oxide production and assisting ammonia clearance after exercise

Key pathways for energy production closely related to migraine include the synthesis of adenosine triphosphate (ATP) through glycolysis, the tricarboxylic acid cycle, and oxidative phosphorylation (Figure 1)

Supplements should be viewed as adjuncts at most, not primary interventions

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