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17,18 A post hoc analysis of LOOK AHEAD trial data found that participants who achieved at least a 10% body weight loss in the first year had a 21% lower rate of major adverse cardiac events

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Typically, Polycomb-induced repression is easy to reverse and dynamic gain and loss of Polycomb- and Trithorax-mediated histone modifications occur during in vitro developmental progression from ESCs to fully differentiated neurons (Mohn et al., 2008

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