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showed that imatinib increases lipid ROS and intracellular Fe2+ levels and dampened glutathione production in gastrointestinal tumor cell lines, another imatinib-sensitive tumor, an effect abrogated by ferrostatin-1, an inhibitor of ferroptosis

Similarly, increased ubiquitylation of proteasome-associated subunits like PSMA1 and PSMB4, and autophagy-related proteins such as sequestosome-1 (SQSTM1) was detected across multiple sites (Fig

Despite sensational and scientifically unfounded claims occasionally seen in the media, WADA is not presently aware of any athletes who are gene doping

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