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Further, bacteria-derived tryptamine, increased by acute stress 107 , can act as a ligand for 5-hyroxytryptamine 4 receptor (5-HT 4 ) expressed in the gut musculature and epithelium modifying secretion and motility 108,109

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PT-141 acts centrally on MC4R neurons of the paraventricular nucleus and preoptic area, triggering the motivational and erectile cascade via neural projections

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We next extended the analysis of single proteins to a cell lysate prepared by freeze-thawing and sonicating human embryonic kidney cells (HEK 293)