doi: 10.1038/s41551-024-01243-1 336 RayensE.RabacalW.KangS
FLNA splice variant-1 showed an increased binding to integrins with respect to wild-type non-spliced FLNA, suggesting that this alternative splicing might function as a regulatory mechanism for the binding of partner proteins to FLNA, with possible implications in pituitary tumors responsiveness to SS/DA analogs
Harjumaki R, Pridgeon CS, Ingelman-Sundberg M (2021) CYP2E1 in alcoholic and non-alcoholic liver injury roles of ROS reactive intermediates and lipid overload
The compounds identified were galangin, kaempferide, -sitosterol, 1-(4-hydroxy-3-methoxyphenyl)-7-phenyl-3,5-heptanediol, 5-hydroxy-7-(4-hydroxyphenyl)-1-phenyl-3-hepta none, 3- O --D-6-palmitoylgluco side (3 R ,5 R )-1-(4-hydroxyphenyl)-7-phenyl-3,5-heptanediol, (5R)-5-hydroxy-7-(4-hydroxy-3-methoxyphenyl)-1-(4-hydroxyphenyl)-3-heptanone, and 5-hy droxy-1-(4-hydroxy-3-methoxyphenyl)-7-(4-hydroxyphenyl)-3-hept anone (Shin et al., 2002)
Moreover, there is a scarcity of studies addressing these effects in bulls