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Patients with unstable cardiovascular disease, poorly controlled hypertension, or significant hypotension may require additional monitoring or alternative therapies

He founded the Metabolic Solutions Institute and its nonprofit arm, dedicated to advancing mental health science

Recent research supports a prion-like propagation model, where pathogenic -synuclein spreads trans-neuronally via exosomes and synaptic transmission, initiating a chain reaction of misfolding across interconnected brain regions

These findings are supported by gene expression data indicating upregulation of lipolytic markers and 3-adrenergic receptor transcripts