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A deeper understanding of these interconnected pathophysiologic mechanisms will facilitate the development of targeted therapies beyond cysteamine, optimizing treatment approaches to mitigate disease progression [146]

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The total course of Accutane usually lasts about twenty weeks

Secondly, in order to preserve residual mitochondrial bioenergetics and positively regulate the body homeostasis/adaptation capacities of these patients, the manuscript will put forward an innovative therapeutic view for the management of the disease, based on a diet with a moderate intake of carbohydrates and enriched in proteins, the practice of exercises of suitable type and intensity and a potential use of dietary supplements (Table 1)

doi: 10.1093/nar/gkx135 10 LaczkDHoganMJToulminSAHicksPLedererKGaudetteBTet al