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Semaglutide encourages weight loss by mimicking a hormone called GLP-1

Nausea from both medications can lead to discomfort, dehydration, or even difficulty maintaining a regular diet, which is important for both weight loss and overall health

Rapid weight loss from any cause increases the risk of gallstone formation, and we do see higher rates of cholelithiasis and cholecystitis in patients on GLP-1 medications, Dr

Brand-name products are mass-manufactured by Novo Nordisk, whereas compounded semaglutide is customized by state-licensed 503A pharmacies

This guide breaks down what the clinical evidence actually shows, explains the indirect mechanisms that could raise your risk, identifies who is most vulnerable, and provides actionable prevention strategies you can start using today