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A typical loading protocol might look like 250mcg to 500mcg administered once per day for the first one to two weeks, or until the desired level of pigmentation is observed in the research model

234 Additionally, GLP-1 can reduce blood glucose production by delaying gastric emptying and decreasing appetite, which also contributes to overall blood glucose control

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Therefore, these studies suggest that DPP-IV inhibitors can beneficially affect the alpha-cell to beta-cell GLP-1R signaling axis for the treatment of diabetes