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(2004, Annals of the New York Academy of Sciences) showed that T4 and its derived fragments greatly upregulate VEGF (vascular endothelial growth factor) expression in endothelial cells, promote endothelial tube formation in Matrigel assays, and reduce ischemic tissue loss in cardiac injury models

As a result, H(3) receptors could be shown as potential targets for future CNS drugs (Fig

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These findings collectively suggest that PTSD-related GABA dysregulation may stem from astrocytes and that MAOB is necessary for PTSD symptoms

Kulkarni SS, Cant C (2015) The molecular targets of resveratrol