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However, the Study To Prevent Non-insulin Dependent Diabetes Mellitus (STOP-NIDDM) trial demonstrated that the -glucosidase inhibitor (GI), acarbose, which specifically prevents postprandial hyperglycemia, reduces the risk of progression of IGT to type two diabetes [9] and CVDs [10]

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Although the existence of mtNOS has been described in mitochondrial fractions from different organs, recent evidence in rat liver mitochondria has questioned the existence of mtNOS, minimizing the contribution of in situ NO generation within mitochondrial to the formation of peroxynitrite (Venkatakrishnan et al., 2009)

Mol Cell Endocrinol