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Over the next several years, as more innovative therapies enter clinical development and commercialization, the GLP-1 field is expected to maintain rapid growth while expanding into broader metabolic disease management

[1] Patients should be advised to maintain adequate fluid intake, particularly if experiencing vomiting or diarrhoea, and to seek medical advice if symptoms are severe or persistent

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Clinical trials have shown that Semaglutide is effective in promoting weight loss

46 The mainstream view holds that the canonical GLP-1 receptor is not expressed in the human liver, and any hepatic effects are likely mediated through extrahepatic mechanisms rather than direct action