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Elysiums own research documented a small but significant increase in cholesterol, but added more studies were needed to determine whether the changes were real or due to chance. One independent study has suggested that a component of NAD may influence the growth of some cancers, but researchers involved in the study warned it was too early to know

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However, human clinical evidence is still limited, and larger, well-controlled trials are needed to clarify safety, efficacy, and appropriate use