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It delivers copper to lysyl oxidase, the enzyme responsible for cross-linking collagen types I and III into durable, organized fibers

Indeed, although many studies have clearly shown that several interventions including pharmacological therapy and lifestyle modifications improve endothelial function under the condition of relatively mild vascular endothelial dysfunction [8,9,10,11,12,13,14,15,16,17,18,19,20,21,22,23,24,25,26,27,28,29,30,31,32,33,34,35], we have shown that advanced endothelial dysfunction is not reversible even by appropriate pharmacological therapy [94]

that when GHRP is administered in vivo at the same dose as GHRH, it releases more GH than the primary neuropeptide, demonstrating the dependence of GHRP upon GHRH for activity